Find hotels in Northeast Missouri, MO from $67

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Our top choices for Northeast Missouri hotels

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1001)
"Very personable staff, easy check in"
United States
Cherie
$97 nightly
The price is $112
Jan 11 - Jan 12, 2026
Total with taxes and fees
Sleep Inn & Suites Hannibal West

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
St. Ann
9.4 out of 10, Exceptional, (2751)
"Great place to stay before your early morning flight. "
United States
Henry
$90 nightly
The price is $106
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn St. Louis Airport

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very Good, (1004)
"Very nice place to stay during a snow storm. "
United States
Teresa
$69 nightly
The price is $80
Jan 11 - Jan 12, 2026
Total with taxes and fees
Quality Inn & Suites Hannibal West

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (847)
"Excellent location, very clean and comfortable, great hot breakfast, and amazing staff!"
United States
Shannon
$110 nightly
The price is $132
Jan 3 - Jan 4, 2026
Total with taxes and fees
Holiday Inn Express & Suites Wentzville St Louis West by IHG

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1606)
"Great place!"
United States
Biju
$92 nightly
The price is $108
Jan 8 - Jan 9, 2026
Total with taxes and fees
The Wildwood Hotel

Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.6 out of 10, Excellent, (1001)
"Great stay! Clean and cozy!!"
United States
Courtney
$101 nightly
The price is $116
Dec 25 - Dec 26
Total with taxes and fees
Best Western On The River

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1001)
"Clean room and friendly staff "
United States
Summer Dawn
$89 nightly
The price is $103
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hampton Inn St. Charles St. Peters

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1005)
"this is the perfect place to stay the night before going to the airport "
United States
Laurie
$129 nightly
The price is $154
Dec 25 - Dec 26
Total with taxes and fees
Hyatt Select St. Louis Airport

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.0 out of 10, Wonderful, (638)
"One of our favorites! This hotel is very clean, breakfast is very good and the kids love the indoor pool."
United States
Debra
$124 nightly
The price is $141
Dec 28 - Dec 29
Total with taxes and fees
Best Western Plus Washington Hotel

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
O'Fallon
8.8 out of 10, Excellent, (719)
"Clean room, quiet"
United States
Laura
$94 nightly
The price is $111
Jan 23 - Jan 24, 2026
Total with taxes and fees
Hilton Garden Inn St. Louis/O'Fallon MO

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
St. Ann
9.2 out of 10, Wonderful, (1504)
"Good transport to and from car rental, a plus "
United States
Ralph
$108 nightly
The price is $127
Dec 28 - Dec 29
Total with taxes and fees
Wingate by Wyndham St. Louis Airport

Depot Inn and Suites

Depot Inn and Suites
3.5 star property
La Plata
9.8 out of 10, Exceptional, (618)
"This place is a hidden gem. Super clean with great staff and well outfitted rooms. "
United States
Johnathan
$83 nightly
The price is $90
Dec 28 - Dec 29
Total with taxes and fees
Depot Inn and Suites

Comfort Inn Sullivan

Comfort Inn Sullivan
2.5 star property
Sullivan
8.6 out of 10, Excellent, (808)
"Nice clean room"
United States
John
$112 nightly
The price is $122
Jan 18 - Jan 19, 2026
Total with taxes and fees
Comfort Inn Sullivan

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (373)
"Room was very clean and great amenities. Breakfast was decent. Great value"
United States
Marcus
$106 nightly
The price is $122
Dec 28 - Dec 29
Total with taxes and fees
Holiday Inn Express & Suites St Peters by IHG

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1000)
"Wonderful stay. Checkin was easy and host was very accommodating. "
United States
Teresa
$78 nightly
The price is $92
Jan 15 - Jan 16, 2026
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (182)
"Clean room, nice staff, great food, and great service "
United States
Thuy
$101 nightly
The price is $117
Dec 26 - Dec 27
Total with taxes and fees
Best Western Plus Fenton

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1001)
"Everything was great!"
United States
Rita
$116 nightly
The price is $134
Jan 18 - Jan 19, 2026
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very Good, (910)
"Very good experience, clean, and friendly staff."
United States
Lijing
$78 nightly
The price is $88
Jan 11 - Jan 12, 2026
Total with taxes and fees
Quality Inn Foristell

Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
2.5 star property
Quincy
8.8 out of 10, Excellent, (449)
"It was in a very quite area and easy to find places to est. able to explore the Mississippi river. "
United States
James
$98 nightly
The price is $111
Jan 23 - Jan 24, 2026
Total with taxes and fees
Quality Inn & Suites Quincy - Downtown

Pinemark Inn & Suites

Pinemark Inn & Suites
2.0 star property
St. Clair
9.6 out of 10, Exceptional, (1000)
"Excellent hotel and they have thought of everything to make your stay wonderful."
United States
Toni
$121 nightly
The price is $132
Jan 18 - Jan 19, 2026
Total with taxes and fees
Pinemark Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Northeast Missouri

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Great live music, sports teams, and popular sights from St. Louis Union Station to Busch Stadium—explore Northeast Missouri, a family-friendly destination also known for its theaters.

Grant\'s Farm which includes heritage architecture

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